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Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes

The aim of our study was to determine whether sildenafil citrate influences the production of Th1- (TNF-α, INF-γ) or Th2-type (TGF-β, IL-10) cytokines by lymphocytes of healthy men. Sildenafil citrate (SC) is a selective blocker of phosphodiesterase 5, by competing for the binding site with cGMP. It...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Zych, Michał, Roszczyk, Aleksander, Kniotek, Monika, Kaleta, Beata, Zagozdzon, Radoslaw
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930755/
https://ncbi.nlm.nih.gov/pubmed/31915712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8478750
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