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Hypophosphatemic Rickets Accelerate Chondrogenesis and Cell Trans-differentiation from TMJ Chondrocytes into Bone Cells via a Sharp Increase in β-Catenin

Dentin matrix protein 1 (DMP1) is primarily expressed in osteocytes, although a low level of DMP1 is also detected in chondrocytes. Removing Dmp1 in mice or a mutation in humans leads to hypophosphatemic rickets (identical to X-linked hypophosphatemia). The deformed skeletons were currently thought...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Li, Hui, Jing, Yan, Zhang, Rong, Zhang, Qi, Wang, Jun, Martin, Aline, Feng, Jian Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930687/
https://ncbi.nlm.nih.gov/pubmed/31751752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115151
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