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Synthesis, Antimicrobial, and Anti-Proliferative Activities of Novel 4-(Adamantan-1-yl)-1-arylidene-3-thiosemicarbazides, 4-Arylmethyl N′-(Adamantan-1-yl)piperidine-1-carbothioimidates, and Related Derivatives

The reaction of 4-(adamantan-1-yl)-3-thiosemicarbazide 3 with various aromatic aldehydes yielded the corresponding thiosemicarbazones 4a–g. 1-Adamantyl isothiocyanate 2 was reacted with 1-methylpiperazine or piperidine to yield the corresponding N-(adamantan-1-yl)carbothioamides 5 and 6, respectivel...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Al-Mutairi, Aamal A., Al-Alshaikh, Monirah A., Al-Omary, Fatmah A. M., Hassan, Hanan M., El-Mahdy, Areej M., El-Emam, Ali A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930481/
https://ncbi.nlm.nih.gov/pubmed/31779091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234308
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