Preparation of Polyethylene Glycol-Ginsenoside Rh1 and Rh2 Conjugates and Their Efficacy against Lung Cancer and Inflammation

Low solubility and tumor-targeted delivery of ginsenosides to avoid off-target cytotoxicity are challenges for clinical trials. In the present study, we report on a methodology for the synthesis of polyethylene glycol (PEG)-ginsenoside conjugates through a hydrolysable ester bond using the hydrophil...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mathiyalagan, Ramya, Wang, Chao, Kim, Yeon Ju, Castro-Aceituno, Verónica, Ahn, Sungeun, Subramaniyam, Sathiyamoorthy, Simu, Shakina Yesmin, Jiménez-Pérez, Zuly Elizabeth, Yang, Deok Chun, Jung, Seok-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930446/
https://ncbi.nlm.nih.gov/pubmed/31795352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234367
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