Increases in PYY and Uncoupling of Bone Turnover Are Associated with Loss of Bone Mass After Gastric Bypass Surgery

CONTEXT: The gut hormones peptide YY (PYY) and ghrelin mediate in part the metabolic benefits of Roux-en-Y gastric bypass (RYGB) surgery. However, preclinical data suggest these hormones also affect the skeleton and could contribute to postoperative bone loss. OBJECTIVE: We investigated whether chan...

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Veröffentlicht in:Bone
Hauptverfasser: Kim, Tiffany Y., Shoback, Dolores M., Black, Dennis M., Rogers, Stanley J., Stewart, Lygia, Carter, Jonathan T., Posselt, Andrew M., King, Nicole J., Schafer, Anne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930344/
https://ncbi.nlm.nih.gov/pubmed/31689523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115115
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