Adaptive amino acid substitutions enable transmission of an H9N2 avian influenza virus in guinea pigs

H9N2 is the most prevalent low pathogenic avian influenza virus (LPAIV) in domestic poultry in the world. Two distinct H9N2 poultry lineages, G1-like (A/quail/Hong Kong/G1/97) and Y280-like (A/Duck/Hong Kong/Y280/1997) viruses, are usually associated with binding affinity for both α 2,3 and α 2,6 si...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Lina, Liu, Saijuan, Chen, Chengyu, Wang, Yuefeng, Lu, Shishan, Dong, Ligong, Chen, Kangkang, Guo, Zhendong, Guo, Jiakai, Li, Jianhui, Zhang, Qingping, Luo, Wenting, Zhang, Yu, Shang, Honglin, Wang, Tengfei, Zhang, Guoyuan, Wen, Jiping, Zhu, Chunmao, Zhang, Meilin, Jin, Yuwei, Gao, Huabin, Shao, Zongzheng, Zhao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930279/
https://ncbi.nlm.nih.gov/pubmed/31875046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56122-6
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