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A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains

Studies on the structures and functions of individual kinases have been used to understand the biological properties of other kinases that do not yet have experimental structures. The key factor in accurate inference by homology is an accurate sequence alignment. We present a parsimonious, structure...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Modi, Vivek, Dunbrack, Roland L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930252/
https://ncbi.nlm.nih.gov/pubmed/31875044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56499-4
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