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In vivo alpha-V beta-3 integrin expression in human aortic atherosclerosis

OBJECTIVES: Intraplaque angiogenesis and inflammation are key promoters of atherosclerosis and are mediated by the alpha-V beta-3 (α(v)β(3)) integrin pathway. We investigated the applicability of the α(v)β(3)-integrin receptor-selective positron emission tomography (PET) radiotracer 18F-fluciclatide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Heart
Hauptverfasser: Jenkins, William S, Vesey, Alex T, Vickers, Anna, Neale, Anoushka, Moles, Catriona, Connell, Martin, Joshi, Nikhil Vilas, Lucatelli, Christophe, Fletcher, Alison M, Spratt, James C, Mirsadraee, Saeed, van Beek, Edwin JR, Rudd, James HF, Newby, David E, Dweck, Marc R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929706/
https://ncbi.nlm.nih.gov/pubmed/31422361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2019-315103
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