A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling

Granzyme B (GrB) is an essential cytotoxic effector in cancer immunotherapy as it can be a potential biomarker to predict the efficacy of immunotherapies including checkpoint inhibitors. Monitoring the Granzyme B activity in cells would help determine a patient's clinical response to treatment...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Briones, Jonathan C., Espulgar, Wilfred V., Koyama, Shohei, Yoshikawa, Hiroyuki, Park, JeongHoon, Naito, Yujiro, Kumanogoh, Atsushi, Tamiya, Eiichi, Takamatsu, Hyota, Saito, Masato
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929635/
https://ncbi.nlm.nih.gov/pubmed/31903110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37728
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