Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2

Bax inhibitor-1 (BI1) conveys anti-apoptotic signals for mitochondria while prohibitin 2 (PHB2) is implicated in sustaining mitochondrial morphology and function. However, their regulatory roles in acute kidney injury (AKI) are largely unknown. Methods: In human patients with AKI, levels of BI1 in u...

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Sparad:
Bibliografiska uppgifter
I publikationen:Theranostics
Huvudupphovsmän: Wang, Jin, Zhu, Pingjun, Li, Ruibing, Ren, Jun, Zhang, Yingmei, Zhou, Hao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2020
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929616/
https://ncbi.nlm.nih.gov/pubmed/31903127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.40098
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