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The ethical challenges raised in the design and conduct of pragmatic trials: an interview study with key stakeholders

BACKGROUND: There is a concern that the apparent effectiveness of interventions tested in clinical trials may not be an accurate reflection of their actual effectiveness in usual practice. Pragmatic randomized controlled trials (RCTs) are designed with the intent of addressing this discrepancy. Whil...

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Bibliographic Details
Published in:Trials
Main Authors: Nicholls, Stuart G., Carroll, Kelly, Zwarenstein, Merrick, Brehaut, Jamie C., Weijer, Charles, Hey, Spencer P., Goldstein, Cory E., Graham, Ian D., Grimshaw, Jeremy M., McKenzie, Joanne E., Fergusson, Dean A., Taljaard, Monica
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929346/
https://ncbi.nlm.nih.gov/pubmed/31870433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3899-x
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