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Endomorphin-2- and Neurotensin- Based Chimeric Peptide Attenuates Airway Inflammation in Mouse Model of Nonallergic Asthma

We examined anti-inflammatory potency of hybrid peptide-PK20, composed of neurotensin (NT) and endomorphin-2 (EM-2) pharmacophores in a murine model of non-atopic asthma induced by skin sensitization with 2,4-dinitrofluorobenzene and intratracheal challenge of cognate hapten. Mice received intraperi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Russjan, Ewelina, Andrzejewski, Kryspin, Sulejczak, Dorota, Kleczkowska, Patrycja, Kaczyńska, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929018/
https://ncbi.nlm.nih.gov/pubmed/31779093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235935
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