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Recent Insights into Long Bone Development: Central Role of Hedgehog Signaling Pathway in Regulating Growth Plate

The longitudinal growth of long bone, regulated by an epiphyseal cartilaginous component known as the “growth plate”, is generated by epiphyseal chondrocytes. The growth plate provides a continuous supply of chondrocytes for endochondral ossification, a sequential bone replacement of cartilaginous t...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Haraguchi, Ryuma, Kitazawa, Riko, Kohara, Yukihiro, Ikedo, Aoi, Imai, Yuuki, Kitazawa, Sohei
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928971/
https://ncbi.nlm.nih.gov/pubmed/31757091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235840
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