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Gonadotropin Releasing Hormone Agonists Have an Anti-apoptotic Effect on Cumulus Cells

Background: Ovaries are sensitive to chemotherapy, which may lead to early depletion of primordial follicle reserve. One strategy for gonadal function preservation is temporary ovarian suppression with Gonadotropin Releasing Hormone agonists (GnRHa) during chemotherapy. To date, GnRHa protective mec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Scaruffi, Paola, Stigliani, Sara, Cardinali, Barbara, Massarotti, Claudia, Lambertini, Matteo, Sozzi, Fausta, Dellepiane, Chiara, Merlo, Domenico Franco, Anserini, Paola, Del Mastro, Lucia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928931/
https://ncbi.nlm.nih.gov/pubmed/31801245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20236045
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