Pemafibrate Prevents Retinal Pathological Neovascularization by Increasing FGF21 Level in a Murine Oxygen-Induced Retinopathy Model

Large-scale clinical trials, such as the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) and the Action to Control Cardiovascular Risk in Diabetes (ACCORD) studies, have shown that the administration of fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist,...

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Udgivet i:Int J Mol Sci
Main Authors: Tomita, Yohei, Ozawa, Nobuhiro, Miwa, Yukihiro, Ishida, Ayako, Ohta, Masayuki, Tsubota, Kazuo, Kurihara, Toshihide
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928689/
https://ncbi.nlm.nih.gov/pubmed/31771164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235878
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