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Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences

Defects in the extracellular matrix protein fibrillin-1 that perturb transforming growth factor beta (TGFβ) bioavailability lead to Marfan syndrome (MFS). MFS is an autosomal-dominant disorder, which is associated with connective tissue and skeletal defects, among others. To date, it is unclear how...

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Foilsithe in:Int J Mol Sci
Main Authors: Altinbas, Lukas, Bormann, Nicole, Lehmann, Daniel, Jeuthe, Sarah, Wulsten, Dag, Kornak, Uwe, Robinson, Peter N., Wildemann, Britt, Kararigas, Georgios
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928642/
https://ncbi.nlm.nih.gov/pubmed/31805661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20236059
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