Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension

There are three critical pathways for the pathogenesis and progression of pulmonary arterial hypertension (PAH): the prostacyclin (prostaglandin I(2)) (PGI(2)), nitric oxide (NO), and endothelin pathways. The current approved drugs targeting these three pathways, including prostacyclin (PGI(2)), pho...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Nakamura, Kazufumi, Akagi, Satoshi, Ejiri, Kentaro, Yoshida, Masashi, Miyoshi, Toru, Toh, Norihisa, Nakagawa, Koji, Takaya, Yoichi, Matsubara, Hiromi, Ito, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928621/
https://ncbi.nlm.nih.gov/pubmed/31771203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235885
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