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Notch3 signalling and vascular remodelling in pulmonary arterial hypertension

Notch signalling is critically involved in vascular morphogenesis and function. Four Notch isoforms (Notch1–4) regulating diverse cellular processes have been identified. Of these, Notch3 is expressed almost exclusively in vascular smooth muscle cells (VSMCs), where it is critically involved in vasc...

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Detalhes bibliográficos
Publicado no:Clin Sci (Lond)
Main Authors: Morris, Hannah E., Neves, Karla B., Montezano, Augusto C., MacLean, Margaret R., Touyz, Rhian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928565/
https://ncbi.nlm.nih.gov/pubmed/31868216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20190835
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