miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia

Oxidative stress is a major cause of adverse outcomes in preeclampsia (PE). Ferroptosis, i.e. programmed cell death from iron-dependent lipid peroxidation, likely mediates PE pathogenesis. We evaluated specific markers for ferroptosis in normal and PE placental tissues, using in vitro (trophoblasts)...

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Pubblicato in:Redox Biol
Autori principali: Zhang, Heng, He, Yue, Wang, Jian-xia, Chen, Ming-hua, Xu, Jian-juan, Jiang, Min-hui, Feng, Ya-ling, Gu, Yan-fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928320/
https://ncbi.nlm.nih.gov/pubmed/31926626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101402
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