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Ceftazidime/avibactam versus standard-of-care agents against carbapenem-resistant Enterobacteriaceae harbouring bla(KPC) in a one-compartment pharmacokinetic/pharmacodynamic model
BACKGROUND: ‘Last-line’ antimicrobial usage has promoted the emergence of MDR bacteria. Production of Klebsiella pneumoniae carbapenemases (KPCs) is increasingly common and leads to resistance to most antimicrobials. However, ceftazidime/avibactam demonstrates activity against KPC-producing strains....
Gespeichert in:
| Veröffentlicht in: | J Antimicrob Chemother |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927864/ https://ncbi.nlm.nih.gov/pubmed/29939267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky213 |
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