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MiR-199a-5p represses the stemness of cutaneous squamous cell carcinoma stem cells by targeting Sirt1 and CD44ICD cleavage signaling

Tumorigenic cancer stem cells (CSCs) exist in various tumors including the cutaneous squamous cell carcinoma (cSCC) as a minor subpopulation and are tightly associated with metastasis and therapeutic resistance. Better understanding of CSCs properties is essential for the novel therapeutic strategy...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Lu, Ruo-Huang, Xiao, Zhi-Qiang, Zhou, Jian-Da, Yin, Chao-Qi, Chen, Zi-Zi, Tang, Feng-Jie, Wang, Shao-Hua
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927716/
https://ncbi.nlm.nih.gov/pubmed/31809227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1689482
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