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MiR-199a-5p represses the stemness of cutaneous squamous cell carcinoma stem cells by targeting Sirt1 and CD44ICD cleavage signaling

Tumorigenic cancer stem cells (CSCs) exist in various tumors including the cutaneous squamous cell carcinoma (cSCC) as a minor subpopulation and are tightly associated with metastasis and therapeutic resistance. Better understanding of CSCs properties is essential for the novel therapeutic strategy...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Lu, Ruo-Huang, Xiao, Zhi-Qiang, Zhou, Jian-Da, Yin, Chao-Qi, Chen, Zi-Zi, Tang, Feng-Jie, Wang, Shao-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927716/
https://ncbi.nlm.nih.gov/pubmed/31809227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1689482
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