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IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function

Lung cancer is the leading cause of cancer-related deaths worldwide. However, tumor suppressor genes remain to be systemically determined for lung cancer. Here we report interferon regulatory factor 8 (IRF8), a member of the IRF family of transcription factors, as a potent lung tumor suppressor gene...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Liang, Jinxia, Lu, Feng, Li, Bo, Liu, Lu, Zeng, Guandi, Zhou, Qian, Chen, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927690/
https://ncbi.nlm.nih.gov/pubmed/31594449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1674053
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