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Heterologous expression, purification and biochemical characterization of a glutamate racemase (MurI) from Streptococcus mutans UA159

BACKGROUND: Glutamate racemase (MurI) is a cofactor-independent enzyme that is essential to the bacterial peptidoglycan biosynthesis pathway and has therefore been considered an attractive target for the development of antimicrobial drugs. While in our previous study the essentiality of the murI gen...

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Publicado en:PeerJ
Autores principales: Wang, Xiangzhu, Chen, Chanchan, Shen, Ting, Zhang, Jiangying
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927343/
https://ncbi.nlm.nih.gov/pubmed/31875162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.8300
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