FOXO3 Transcription Factor Regulates IL-10 Expression in Mycobacteria-Infected Macrophages, Tuning Their Polarization and the Subsequent Adaptive Immune Response

Alveolar Macrophages play a key role in the development of a robust adaptive immune response against the agent of Tuberculosis (TB), Mycobacterium tuberculosis (M.tb). However, macrophage response is often hampered by the production of IL-10, a potent suppressor of the host immune response. The secr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bouzeyen, Rania, Haoues, Meriam, Barbouche, Mohamed-Ridha, Singh, Ramandeep, Essafi, Makram
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927284/
https://ncbi.nlm.nih.gov/pubmed/31921181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02922
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