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Parameter, noise, and tree topology effects in tumor phylogeny inference

BACKGROUND: Accurate inference of the evolutionary history of a tumor has important implications for understanding and potentially treating the disease. While a number of methods have been proposed to reconstruct the evolutionary history of a tumor from DNA sequencing data, it is not clear how aspec...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Tomlinson, Kiran, Oesper, Layla
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927103/
https://ncbi.nlm.nih.gov/pubmed/31865909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0626-0
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