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The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae

HAMLET is a complex of human α-lactalbumin (ALA) and oleic acid and kills several Gram-positive bacteria by a mechanism that bears resemblance to apoptosis in eukaryotic cells. To identify HAMLET's bacterial targets, here we used Streptococcus pneumoniae as a model organism and employed a prote...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roche-Hakansson, Hazeline, Vansarla, Goutham, Marks, Laura R., Hakansson, Anders P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926454/
https://ncbi.nlm.nih.gov/pubmed/31694917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009930
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