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Overexpression of Na(+)/H(+) exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK
Understanding the specific properties of human induced pluripotent stem cells (iPSCs) is important for quality control of iPSCs. Having incidentally discovered that overexpression of plasma membrane Na(+)/H(+) exchanger 1 (NHE1) induces cell death in iPSCs, we investigated the mechanism of NHE1-indu...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926445/ https://ncbi.nlm.nih.gov/pubmed/31723030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010329 |
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