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Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain

Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined “class I″ viral glycoproteins, the formation of a highly stable α-helical bundle by the ectodomain of the fusion subunit (e.g., GP2 for Marburg virus, MARV) is postulated to provid...

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Bibliografiske detaljer
Udgivet i:Heliyon
Main Authors: Liu, Nina, Girvin, Mark E., Brenowitz, Michael, Lai, Jonathan R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926192/
https://ncbi.nlm.nih.gov/pubmed/31890962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e03018
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