Epigenetic Inactivation of SOX30 Is Associated with Male Infertility and Offers a Therapy Target for Non-obstructive Azoospermia

Non-obstructive azoospermia (NOA) is the most severe form of male infertility. However, the etiology of NOA is largely unknown, resulting in a lack of clinical treatments. Here, we performed a comparative genome-wide profiling of DNA methylation and identified SOX30 as the most notably hyper-methyla...

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書誌詳細
出版年:Mol Ther Nucleic Acids
主要な著者: Han, Fei, Jiang, Xiao, Li, Zhi-ming, Zhuang, Xuan, Zhang, Xi, Ouyang, Wei-ming, Liu, Wen-bin, Mao, Cheng-yi, Chen, Qing, Huang, Chuan-shu, Gao, Fei, Cui, Zhi-hong, Ao, Lin, Li, Yan-feng, Cao, Jia, Liu, Jin-yi
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926170/
https://ncbi.nlm.nih.gov/pubmed/31835093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.038
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