MAIT Cells Are Major Contributors to the Cytokine Response in Group A Streptococcal Toxic Shock Syndrome

Streptococcal toxic shock syndrome (STSS) is a rapidly progressing, life-threatening, systemic reaction to invasive infection caused by group A streptococci (GAS). GAS superantigens are key mediators of STSS through their potent activation of T cells leading to a cytokine storm and consequently vasc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Emgård, Johanna, Bergsten, Helena, McCormick, John K., Barrantes, Israel, Skrede, Steinar, Sandberg, Johan K., Norrby-Teglund, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926028/
https://ncbi.nlm.nih.gov/pubmed/31772015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910883116
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