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Improving single-cell transcriptome sequencing efficiency with a microfluidic phase-switch device

In this paper, we present a novel method to improve the efficiency of single-cell transcriptome sequencing for analyzing valuable cell samples. The microfluidic device we designed integrates multiple single-cell isolation chambers with hydrodynamic traps and achieves a nearly 100% single-cell captur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Analyst
Hauptverfasser: Zhang, Baoyue, Xu, Hong, Huang, Yuqing, Shu, Weiliang, Feng, Hongtao, Cai, Jin, Zhong, Jiang F., Chen, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925944/
https://ncbi.nlm.nih.gov/pubmed/31688860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9an00823c
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