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Mimicking nature-made beta cells: recent advances towards stem cell-derived islets

PURPOSE OF REVIEW: Stem cell-derived islets are likely to be useful as a future treatment for diabetes. However, the field has been limited in the ability to generate β-like cells with both phenotypic maturation and functional glucose-stimulated insulin secretion that is similar to primary human isl...

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Detalhes bibliográficos
Publicado no:Curr Opin Organ Transplant
Main Authors: Tremmel, Daniel M., Mitchell, Samantha A., Sackett, Sara D., Odorico, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925596/
https://ncbi.nlm.nih.gov/pubmed/31433306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000687
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