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Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model

It is accepted that insulin-secreting β-cells release insulin in response to glucose even in the absence of functional ATP-sensitive K(+) (K(ATP))-channels, which play a central role in a ‘consensus model’ of secretion broadly accepted and widely reproduced in textbooks. A major shortcoming of this...

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Bibliographic Details
Published in:Biochem Soc Trans
Main Authors: Di Fulvio, Mauricio, Aguilar-Bryan, Lydia
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925527/
https://ncbi.nlm.nih.gov/pubmed/31697318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190513
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