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LRRK2 regulation of immune-pathways and inflammatory disease

Mutations in the leucine-rich-repeat kinase 2 (LRRK2) gene are associated with familial and sporadic cases of Parkinson's disease but are also found in immune-related disorders such as inflammatory bowel disease, tuberculosis and leprosy. LRRK2 is highly expressed in immune cells and has been f...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Wallings, Rebecca L., Tansey, Malú G.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925522/
https://ncbi.nlm.nih.gov/pubmed/31769472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20180463
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