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Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor

BACKGROUND: Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear. Because the production of autoantibodies, formation and deposition of immunocomplexes are major serological characte...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Yang, Chunshu, Hou, Xiaoyu, Feng, Qianhui, Li, Yingzhuo, Wang, Xuejiao, Qin, Ling, Yang, Pingting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925475/
https://ncbi.nlm.nih.gov/pubmed/31864410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02175-0
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