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Installation of Minimal Tetrazines Through Silver-mediated Liebeskind-Srogl Coupling with Arylboronic Acids

Described is a general method for the installation of a minimal 6-methyltetrazin-3-yl group via the first example of a Ag-mediated Liebeskind-Srogl cross-coupling. The attachment of bioorthogonal tetrazines on complex molecules typically relies on linkers that can negatively impact the physiochemica...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lambert, William D., Fang, Yinzhi, Mahapatra, Subham, Huang, Zhen, am Ende, Christopher W., Fox, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925384/
https://ncbi.nlm.nih.gov/pubmed/31603679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08677
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