Commensal bacteria regulate regionalization of acute norovirus infection along the intestinal tract through bile acid-mediated priming of type III interferon

Accumulating evidence demonstrates that the intestinal microbiota enhance mammalian enteric virus infections. For example, we and others have previously reported that commensal bacteria stimulate acute and persistent murine norovirus infections. In apparent contradiction to these results however, th...

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Udgivet i:Nat Microbiol
Main Authors: Grau, Katrina R., Zhu, Shu, Peterson, Stefan T., Helm, Emily W., Philip, Drake, Phillips, Matthew, Hernandez, Abel, Turula, Holly, Frasse, Philip, Graziano, Vincent R., Wilen, Craig B., Wobus, Christiane E., Baldridge, Megan T., Karst, Stephanie M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925324/
https://ncbi.nlm.nih.gov/pubmed/31768030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0602-7
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