Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Microglia survey brain parenchyma, responding to injury and infections. Microglia also respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process remains unclear. Using simultaneous in vivo imaging, we demonstrated that systemic inflammation induces CCR5-depende...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Haruwaka, Koichiro, Ikegami, Ako, Tachibana, Yoshihisa, Ohno, Nobuhiko, Konishi, Hiroyuki, Hashimoto, Akari, Matsumoto, Mami, Kato, Daisuke, Ono, Riho, Kiyama, Hiroshi, Moorhouse, Andrew J., Nabekura, Junichi, Wake, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925219/
https://ncbi.nlm.nih.gov/pubmed/31862977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13812-z
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