Mutational change of CTX‐M‐15 to CTX‐M‐127 resulting in mecillinam resistant Escherichia coli during pivmecillinam treatment of a patient

Pivmecillinam (amdinocillin pivoxil) is the recommended first‐choice antibiotic used to treat urinary tract infections (UTIs) in Denmark. The frequency of mutation to mecillinam (MEC) resistance is described as high in vitro; however, treatment of UTI has a good clinical response and prevalence of m...

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Publicado no:Microbiologyopen
Main Authors: Nielsen, Karen Leth, Hansen, Katrine Hartung, Nielsen, Jesper Boye, Knudsen, Jenny Dahl, Schønning, Kristian, Frimodt‐Møller, Niels, Hertz, Frederik Boëtius, Jansåker, Filip
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925186/
https://ncbi.nlm.nih.gov/pubmed/31573735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.941
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