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A prospective, open-label, interventional study protocol to evaluate treatment efficacy of nivolumab based on serum-soluble PD-L1 concentration for patients with metastatic and unresectable renal cell carcinoma

INTRODUCTION: Nivolumab has been proven to prolong overall survival as a second-line therapy for patients with advanced renal cell carcinoma (RCC) in a phase III clinical trial. However, versatile biomarkers have not been established to predict the efficacy of nivolumab against target disease. METHO...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Bando, Yukari, Hinata, Nobuyuki, Omori, Takashi, Fujisawa, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924736/
https://ncbi.nlm.nih.gov/pubmed/31826889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-030522
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