Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs

Lassa virus (LASV), the causative agent of Lassa fever (LF), was first identified in 1969. Since then, outbreaks in the endemic countries of Nigeria, Liberia, and Sierra Leone occur on an annual basis resulting in a case-fatality rate of 15-70% in hospitalized patients. There is currently no license...

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Pubblicato in:Vaccine
Autori principali: Maruyama, Junki, Mateer, Elizabeth J., Manning, John T., Sattler, Rachel, Seregin, Alexey V., Bukreyeva, Natalya, Jones, Frank R., Balint, Joseph P., Gabitzsch, Elizabeth S., Huang, Cheng, Paessler, Slobodan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924625/
https://ncbi.nlm.nih.gov/pubmed/31561999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.09.030
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