Impact of Minimal Residual Disease Detection by Next-Generation Flow Cytometry in Multiple Myeloma Patients with Sustained Complete Remission after Frontline Therapy

Minimal residual disease (MRD) was monitored in 52 patients with sustained CR (≥2 years) after frontline therapy using next-generation flow (NGF) cytometry. 25% of patients initially MRD- reversed to MRD+. 56% of patients in sustained CR were MRD+; 45% at the level of 10(−5); 17% at 10(−6). All pati...

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Détails bibliographiques
Publié dans:Hemasphere
Auteurs principaux: Terpos, Evangelos, Kostopoulos, Ioannis V., Kastritis, Efstathios, Ntanasis-Stathopoulos, Ioannis, Migkou, Magdalini, Rousakis, Pantelis, Argyriou, Alexandra T., Kanellias, Nikolaos, Fotiou, Despina, Eleutherakis-Papaiakovou, Evangelos, Gavriatopoulou, Maria, Ziogas, Dimitrios C., Papanota, Aristea-Maria, Spyropoulou-Vlachou, Marilyn, Trougakos, Ioannis P., Tsitsilonis, Ourania E., Paiva, Bruno, Dimopoulos, Meletios A.
Format: Artigo
Langue:Inglês
Publié: Wolters Kluwer Health 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924563/
https://ncbi.nlm.nih.gov/pubmed/31976475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000300
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