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Few SINEs of life: Alu elements have little evidence for biological relevance despite elevated translation

Transposable elements colonize genomes and with time may end up being incorporated into functional regions. SINE Alu elements, which appeared in the primate lineage, are ubiquitous in the human genome and more than a thousand overlap annotated coding exons. Although almost all Alu-derived coding exo...

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Détails bibliographiques
Publié dans:NAR Genom Bioinform
Auteurs principaux: Martinez-Gomez, Laura, Abascal, Federico, Jungreis, Irwin, Pozo, Fernando, Kellis, Manolis, Mudge, Jonathan M, Tress, Michael L
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924539/
https://ncbi.nlm.nih.gov/pubmed/31886458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqz023
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