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AFM nanoindentation reveals decrease of elastic modulus of lipid bilayers near freezing point of water

Cell lipid membranes are the primary site of irreversible injury during freezing/thawing and cryopreservation of cells, but the underlying causes remain unknown. Here, we probe the effect of cooling from 20 °C to 0 °C on the structure and mechanical properties of 1,2-dipalmitoyl-sn-glycero-3-phospho...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Gabbutt, Calum, Shen, Wuyi, Seifert, Jacob, Contera, Sonia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923397/
https://ncbi.nlm.nih.gov/pubmed/31857622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55519-7
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