Mesoporous Silica Nanoparticle–Based Combination of NQO1 Inhibitor and 5-Fluorouracil for Potent Antitumor Effect Against Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and neck squamous cell carcinomas (HNSCC) are one of the deadliest forms of cancer, and 90% of its origin is from squamous cells. NAD(P)H:quinone oxidoreductase 1 (NQO1), an enzyme overexpressed in squamous cell carcinoma, plays an important role in proliferation and chemoresistance. The main a...

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Detalhes bibliográficos
Publicado no:Nanoscale Res Lett
Main Authors: Chen, Jing, Zhang, Shuzhen, Zhang, Shuai, Gao, Shanjun, Wang, Jianbo, Lei, Dongchun, Du, Pengqiang, Xu, Zhiwei, Zhu, Cailiang, Sun, Hongbin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Nano Express
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923313/
https://ncbi.nlm.nih.gov/pubmed/31858276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11671-019-3224-3
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