Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1)-mediated DNA episomal genome replication and persistence are essential for the viral pathogenesis. Cyclophilin A (CYPA) is upregulated in EBV-associated nasopharyngeal carcinoma (NPC) with unknown roles. In the present approach, cytosolic CYPA was f...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Xin, Shuyu, Du, Shujuan, Liu, Lingzhi, Xie, Yan, Zuo, Lielian, Yang, Jing, Hu, Jingjin, Yue, Wenxing, Zhang, Jing, Cao, Pengfei, Zhu, Fanxiu, Lu, Jianhong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923202/
https://ncbi.nlm.nih.gov/pubmed/31921057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02879
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