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A cell-based probabilistic approach unveils the concerted action of miRNAs
Mature microRNAs (miRNAs) regulate most human genes through direct base-pairing with mRNAs. We investigate the underlying principles of miRNA regulation in living cells. To this end, we overexpressed miRNAs in different cell types and measured the mRNA decay rate under a paradigm of a transcriptiona...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6922470/ https://ncbi.nlm.nih.gov/pubmed/31790387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007204 |
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