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Can Combination MEK and Akt Inhibition Slay the Giant Congenital Nevus?

The clinical management of large and giant congenital melanocytic nevi (lgCMN) relies heavily upon iterative surgical procedures. In this issue Rouille et al. (2019) use lgCMN explants and a newly developed patient-derived xenograft model to show that the local administration of MEK and Akt inhibito...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Murphy, Brandon M., Burd, Christin E.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921933/
https://ncbi.nlm.nih.gov/pubmed/31445573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.04.009
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