Clearance of Staphylococcus aureus from In Vivo Models of Chronic Infection by Immunization Requires Both Planktonic and Biofilm Antigens

Staphylococcus aureus is a causative agent of chronic biofilm-associated infections that are recalcitrant to resolution by the immune system or antibiotics. To combat these infections, an antistaphylococcal, biofilm-specific quadrivalent vaccine against an osteomyelitis model in rabbits has previous...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Harro, Janette M., Achermann, Yvonne, Freiberg, Jeffrey A., Allison, Devon L., Brao, Kristen J., Marinos, Dimitrius P., Sanjari, Salar, Leid, Jeff G., Shirtliff, Mark E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921670/
https://ncbi.nlm.nih.gov/pubmed/31712267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00586-19
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