Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

BACKGROUND: Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, that is conferred by mutations in the dhfr and dhps genes. The World Health Organ...

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Veröffentlicht in:Malar J
Hauptverfasser: van Lenthe, Marit, van der Meulen, Renske, Lassovski, Maryvonne, Ouabo, Adelaide, Bakula, Edwige, Badio, Colette, Cibenda, Deogratias, Okell, Lucy, Piriou, Erwan, Grignard, Lynn, Lanke, Kjerstin, Rao, Bhargavi, Bousema, Teun, Roper, Cally
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921399/
https://ncbi.nlm.nih.gov/pubmed/31852480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-3057-7
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